The CRPS Institute
Comprehensive Care for Complex Pain
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A carefully selected group of speciality physicians comes together to treat CRPS patients.
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CBS News Story
A new development has found a way for patients suffering from the condition known as Complex Regional Pain Syndrome (CRPS) to relieve their pain and stress. Ketamine infusions are being suggested as a safe and effective option for treating this condition. When taken in small doses, it is considered a more effective choice than using large doses of narcotics.
Ketamine has long been known to be able to inhibit the activity of the N-Methyl-D-aspartate (NMDA) receptor. It is thought that the NMDA receptors in CRPS patients are hypersensitive or overactive and are significant source of the chronic pain associated with CRPS.
The NMDA receptor is a neurotransmitter that is responsible for receiving and transmitting pain signals in the spinal cord and brain. These neurotransmitters are located in the synapses throughout the central nervous system. When electrical stimulation, such as pain signals, are interpreted by the brain a chemical known as glutamate is released. Misfiring NMDA receptors interpret this release of glutamate as a painful stimulus and react by sending pain signals to the brain.
Smaller doses of ketamine have a greater effect on the pain that comes with CRPS, without causing any dependency or sedation. Because of this, a patient would be able to receive the treatment as an outpatient and be able to live more comfortably at home. Also, it is also easier on the wallet as lengthy hospitalizations make for lengthier hospital bills.
CRPS is intractable and often will lead to major depression. Ketamine is known to have a significant effect on treating depression, as well. Ketamine therapy began to decline after physicians had trouble figuring out dosages but has made a resurgence as physicians have garnered more information on proper dosing.
For many, CRPS has disrupted many aspects of their life. For that reason, the CRPS Institute offers more than just physical care. The CRPS Institute team includes the most renowned specialists in the fields of Interventional Pain Management, Anesthesiology, Physical and Occupational Therapy and Mental Health.
Complex Regional Pain Syndrome (CRPS) is a chronic pain disease which involves severe pain, swelling and changes to the skin. The disease comes in unique forms. The first is a chronic nerve disorder that occurs most often in the arms or legs after a minor injury. The second is caused by an injury to the nerve. The damaged nerves are unable to control the blood flow throughout the body causing the pain and swelling.
Stage 1 consists of a variety of different symptoms. They are: Changes in skin temperature (going between warm and cold), faster growth of nails and hair, severe burning and/or aching that worsens by the touch, pain in the joints, muscles spasms, perspiring more often and skin becoming spotty or blotchy. People do often remain in Stage 1.
Stage 2 comes after 2-3 months of experiencing stage 1. The skin will continue to go through abnormal changes. Finger and toe nails will crack and break easily and hair begins to grow slowly instead of quickly. The joint pain, weak muscles and overall pain will be there as well.
When a person has moved on to stage 3, there are some irreversible problems that arise. First, there will be severe muscle contraction, which will limit movement in all limbs. Another common problem is neurogenic atrophy, which limits muscle use because of nerve damage. This tends to happen suddenly.
Early diagnosis is very important when it comes to CRPS, because while the disease cannot be cured, it can be slowed considerably. The first move to be made is to contact the CRPS Institute in New York City. At The CRPS Institute, we know that the symptoms of CRPS are not just physical. Our goal is to help you recover all aspects of your life and return you to a healthy and active lifestyle. The CRPS Institute team includes the most renowned specialists in the fields of Interventional Pain Management, Anesthesiology, Physical and Occupational Therapy and Mental Health.